Sentence examples for leading the initiation from inspiring English sources

Extensive research has focused on the discovery of genes that control the highly complex regulatory mechanisms leading the initiation and regulation of embryogenesis [ 5, 10- 13].

It remains to be conclusively determined whether healthy adult stem cells undergo oncogenic transformation leading to the initiation of tumorigenesis, or whether healthy airway cells undergo oncogenic transformation leading to their de-differentiation and subsequent adoption of stem cell-like properties.

Despite decades of research, the events leading to the initiation of labour in humans remain unclear.

The first step leading to the initiation of the immune system cascade is recognition.

When InSb layer is deposited, InSb is incorporated onto the side face and top surface of InAs NWs, leading to the initiation of InSb NWs.

The discovery that specific oxidative metabolites of estrogens, the catechol estrogen quinones, react with DNA supports the hypothesis that estrogens can become endogenous carcinogens by generating the mutations leading to the initiation of cancer [11 14].

The hardness characteristics created by the Al2Cu intermetallic compounds result in increased brittleness in the weld metal, which can act as a stress raiser leading to the initiation of cracks.

The rational design of Th1 adjuvants can also benefit from our better understanding of the nature of proinflammatory signals leading to the initiation of both innate and adaptive immune effector mechanisms.

Only recently, it was discovered that flux cancellation appeared to be a key part of magnetic evolution leading to the initiation of coronal mass ejections (CMEs) [Zhang et al., Magnetic flux cancellation associated withthe major solar event on 2000 July 14. Astrophys. J. 548, L99 102, 2001; Zhang et al., 2001b. Filament-associated halo coronal mass ejection, Chin. J. Astron.

Therefore, the activation of p53 causes a functional disorder of the reduction/oxidation reaction within the mitochondria, leading to the initiation of the caspase cascade, which is the downstream process of the apoptosis induction system.

Indeed the activity of OVs involves not only replication in, and destruction of tumour cells but also the recruitment of host immune cells to the tumour bed leading to the initiation of anti-tumour immunity.