The instability of metastatic tumors remains a leading obstacle to personalization, because information from a patient's primary tumor may not accurately reflect the metastasis, and one metastasis may vary from another.
Earlier this year, a Northwestern Mutual study showed that 45percentt of Americans think health care costs are the leading obstacle to a financially secure retirement.
The AMA has been the leading obstacle to progressive health care reform for nearly a century -- tracing all the way back to Theodore Roosevelt, the first American president to call for universal health coverage.
In a qualitative study from Uganda, Tanzania, and Malawi, hunger during HAART initiation emerged as a leading obstacle to ARV adherence [13].
In the qualitative study from Uganda, South Africa, Tanzania, and Malawi, hunger during HAART initiation emerged as a leading obstacle to ARV adherence [ 7].
Blumenthal and colleague [ 4] argue that a leading obstacle to achieving quality in health care is the absence of a " business case" for quality.
Once capable of running, lesioned rats badly performed the obstacle clearance task with their contralesional limbs when these limbs were leading the obstacle manoeuvre.
Despite the ratings decline for "Wipeout," its producers said that they believed that they could keep the show going for years by creating more extravagant obstacles, leading to more dramatic belly-flops and falls.
In "Rockettes to the Rescue" Ms. Haberman has choreographed a video game in which the Rockettes help a mother and daughter battle their way through four levels of obstacles, leading to the archvillain: the Humbug King.
