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Vascularization is a leading limitation for the clinical application of in vitro engineered tissue constructs because of the insufficient blood supply in the initial phase after implantation.
4, 5 The leading limitation to intensive glucose lowering is the increased risk for hypoglycemia.
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However, after slow progression of the disease to a more advanced stage, namely, CAS, impaired leaflet motion with severe calcium deposition in the valve leaflet occurs, subsequently leading to limitation of blood flow through the valve [ 2].
It has been hypothesised that the prevention of excessive release of pro-inflammatory cytokines [ 15], and activation of proteolytic pathways leading to limitation of free-radical generation [ 16] may inhibit the catabolic skeletal muscle changes in sepsis [ 17] and thus critical illness weakness syndromes.
In multivariate analyses, they found that the highest risks for pain conditions leading to limitation in physical activity for the female personnel were work in awkward postures, both in relation to neck-shoulder (OR 3.0), and low back pain (OR 1.9).
However, this model restricts the translational motion model, leading to limitations on specific scenarios.
However, this model restricts the rotational motion model, leading to limitations on specific scenarios, such as the space target and the civil aviaton aircraft moving stably.
Still, there are considerable variations in how the method is currently used, leading to limitations in comparing the results and the conclusions that can be drawn.
The current understanding of urban green space (UGS) recreational service is limited due to the lack of being examined under the logic that underlies the ecosystem service paradigm, leading to limitations in the application of ecosystem based management in urban land use planning.
Adherent methods currently employed for ES cell culture are unable to provide a suitable culture system due to the heterogeneous static conditions, resulting in batch-to-batch variation, labour intensive methodology and ultimately, restricted cell number due to the available surface area, leading to limitations in scalability [7] [9].
Patellofemoral pain (PFP) can cause significant pain leading to limitations in societal participation and physical activity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com