Sentence examples for leading invasive from inspiring English sources

Our own recent work suggests that by inhibiting the interaction between cancer cell and TME - in particular, Fibronectin, which was predominately produced by those cells at the leading invasive edge of the tumor, inhibits their migratory capacity - metastasis can be blocked (summarized in [5]).

Interestingly, enhanced metastasis in the absence of a carcinoma cell response to TGF-β stimulation has been shown to involve increased chemokine production resulting in recruitment of pro-metastatic myeloid derived suppressor cell (MDSC) populations to the tumor microenvironment at the leading invasive edge.

Since its emergence in the 1970s, GBS disease has been the leading invasive bacterial infection associated with illness and death among newborns in the United States.

This paradoxical result might reflect the decreased vascular density in the leading invasive front where we microdissected the stroma relative to the stroma surrounding DCIS.

In line with previous studies, membranous PODXL expression was predominantly observed in subsets of tumour cells at the leading invasive front (Larsson et al, 2011; Dallas et al, 2012; Larsson et al, 2012b).

It has also been proposed that small pericellular gradients can form around cells dispersed in a matrix (like what is seen at the leading invasive edge of a solid tumor) to yield a chemokine gradient across the body of the cell.

In contrast to invasive aspergillosis, Candida infections of mucosal membranes are a frequent complication of GC treatment, although leading to invasive candidiasis only very rarely.

Some currently invaded lands may also become climatically unsuitable, potentially leading an invasive species to retreat from invaded areas [8].

They found that resource heterogeneity was amplified by cellular proliferation and migration, leading to invasive tumor morphologies.

Expression of NRF2-regulated anti-oxidant/glutathione metabolic gene HMOX1, and NCF1 (the p47phox subunit of NADPH oxidase, a major cellular source of ROS) is up-regulated in CIS lesions, but is also relatively high in precancerous lesions (Figure 4, Table S2), suggesting that xenobiotic/oxidative stress may initiate early in the pathway leading to invasive lung cancer.

Cervical intraepithelial neoplasia (CIN) is a premalignant disease, often leading to invasive cervical cancer [ 1].