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They are highly dynamic structures, fast assembled and disassembled to allow progression of the cell leading edge toward the migratory stimuli.
It should be realistic but instill a sense of purpose while having a leading edge toward tomorrow's vision.
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Monomeric actin is recruited at the leading edge and moves toward the rear in a 'treadmilling' process that does not change the breadth of the pseudopod (Wang, 1985).
The loss of directionality of dynamic MTs that moved across the growth cone rather than toward the leading edge was thought to lead to the eventual formation of MT loops characteristic of large pausing growth cones (Dent et al., 1999).
He added, "It kind of leads us toward the leading edge".
The tectrices cover the bases of the remiges, overlapping and decreasing in size toward the leading edge of the wing.
Similarly, in case of the wing driven at 10 m/s, the flow separation was growing up from the trailing edge area toward the leading edge area.
In our findings, it remains elusive whether filopodia appeared first and some of them guided the formation of lamellipodia or if lateral filopodia were probing microenvironment during cell migration toward the leading edge (where the lamellipodia is).
The results reveal that the copper disk leans down toward the leading edge and produces a negative-dominated (approximately 70%) fluid pressure, which differs from the multi-zone carrier but agrees with other studies in which the fluid pressure is measured from the disk side.
A previous study described a subset of microtubules that are derived from the trans Golgi network that preferentially orient toward the leading edge of motile cells [23].
The Golgi apparatus identified by the staining of the protein Golgin 97 was polarised toward the leading edge in 73% of the migrating cells (Figure 9B).
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