When the range expansion occurred, a lower overall proportion of the total genetic variation was carried along the leading edge of the expansion event.
Being a potent proto-oncogene and bona fide central regulator of several signal transduction pathways in many human cancers, Ras is at the leading edge of most tumorigenic events and is activated in as many as 50% of all HCC cases (Downward, 2003; Villanueva and Llovet, 2011).
The leading edge speed of the SEP events (1255 km/s) is larger than non-SEP events (926 km/s), even when comparing events with similar flare associations.
Mission managers called up to the crew to alert them of the find, advising Altman ("Scooter") that one of the orbiter's wing leading edge sensors recorded a debris event during ascent, around 104 – 106 seconds following liftoff, which may have been the cause of the damage seen in that area.
Ligand activation of chemokine receptors activates PI3-Kinase, which generates phosphatidylinositol-tris- 3,4,5 phosphate (phosphatidylinositol-tris- 3,4,5 phosphateevent phosphatidylinositol-tris- 3,4,5 phosphate directionatitheof the celeadingation [37]–[39].
We considered that the role of Chp might involve events at the leading edge of the envelope layer (EVL) or yolk syncytial layer (YSL) cell margin during migration phase of epiboly.
The results of the present study are in agreement with the previously published studies describing localized Ca2+ signalling events at the leading edge of migrating cells [ 14, 15].
Further investigation of events at the leading edge of T cells is needed to decide how close the parallels are with the spreading dynamics of fibroblasts.
This model system is such that it allows for the spatial mapping of gene expression profiles within the mantle to patterning and structural events at the leading edge of the shell.
We see that the effect of leading edge saturation is to establish a new effective leading edge for new captures.
Leading edge of the lumen intima interface to leading edge of the media adventitia defined cIMT.
