Your English writing platform
Discover LudwigExact(2)
In contrast, Drosophila DC is not characterized by marked specializations within the EE domain and the prominent embryonic F-actin fibers are part of the highly structured epidermal leading edge cell row.
Although Rac1 is known to establish cell polarity by inducing cytoskeletal changes specifically in the leading edge, cell polarity is perturbed at higher levels of Rac1 activity as a result of cytoskeletal changes induced in the entire cell (Pankov et al, 2005).
Similar(58)
Danjo Y, Gipson IK. Specific transduction of the leading edge cells of migrating epithelia demonstrates that they are replaced during healing.
The behaviors of prechordal plate leading edge cells at 90% epiboly were also analyzed for extension abnormality.
The rear area of the leading edge cells were in close contact with other cells that might help to maintain cell polarity in the absence of Ptenb [38].
In StdMO morphants, prechordal plate cells formed multiple layers and migrated as a sheet with the leading edge cells formed protrusions at front and adhered cells in the back.
The average distance covered by leading edge cells (measured in terms of percentage of wound covered in 2 hours) is shown for control versus 3 DAAM1 expressing lines (Fig. 6D).
We therefore wounded one cell row in front of the engrailed-expressing cells (Fig. 4C) so that leading edge cells are wild type and pull normally on Sqh RNAi neighbouring cells behind them.
In Xenopus NC outgrowths, leading edge cells extended large, polarised lamellipodia whereas those with defective PCP signalling failed to polarise (Carmona-Fontaine et al., 2008; De Calisto et al., 2005).
We investigated zipping dynamics and found that apposing leading edge cells come together at their apical ends and then square off basally to form a lateral junction.
Images of typical leading edge cells of the mCherry-DAAM1 lines are shown in Fig. S2.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com