Exact(1)
Rheumatoid arthritis synovial fibroblasts (RASFs; also termed fibroblast-like synoviocytes or type B synoviocytes), together with synovial macrophages, are the two leading cell types in the terminal layer of the hyperplastic synovial tissue that invades and degrades adjacent cartilage and bone.
Similar(59)
Despite these issues, the MCFC has emerged as one of the leading commercial fuel cell types.
As development progresses, each of these quasi-stable states is modified and stabilized, leading to differentiated cell types.
However, improved and more reliable differentiation protocols leading to transplantable cell types that integrate into their natural niches in vivo, e.g. engraftable HSC, will have to be developed (Suzuki et al, 2013).
Competence is another stationary-phase differentiation process leading a cell-type to allow uptake of foreign DNA.
In support of this hypothesis, caveolin-1 is shown to interact and potentiate the activity of metalloproteinases (Puyraimond et al, 2001) and the urokinase receptor (Stahl and Mueller, 1995; Wei et al, 1999) in a variety of cell types, leading to activation of cell surface plasminogen, and generation of plasmin, which in turn leads to the overall degradation of extracellular matrices.
During this process, the cytoskeletal proteins have been found to be either damaged and/or enzymatically disassembled in several cell types, leading to formation of apoptotic manifestations.
Intestinal ischemia and reperfusion injury can accelerate complex processes between the endothelium and different cell types leading to microvascular injury, cellular necrosis, and apoptosis.
The aging of specific cell(s) inflames surrounding cells of the same and other cell types leading to tissue degeneration, and continuous accumulation results in irreversible losses of differentiated function and pathological changes of the diseased tissue.
ROCK-2 phosphorylates moesin on Thr558 in different cell types, leading to filamentous actin fibers polymerization [20].
Such blebs (usually transient) are also seen near the leading edge in other cell types and are due to myosin-generated pressure gradients and associated hydraulic flows [7].
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