To mine out the cancer relevant genes, we performed leading edge analysis of gene set enrichment (GSEA) analysis tool [ 21].
The largest up-regulated category in the GSEA leading edge analysis of the ECACC-6 and Nf1-Mouse-12 groups is cell cycle/mitosis/cytokinesis (e.g. CDC20, CDC2, FOXM1, MCM3, MCM6, MCM2, CCNB2 - Additional file 4).
To identify the potential cancer-relevant genes in UTUC, we performed leading edge analysis of GSEA to identify the genes that are significantly aberrant in cancer pathways and correlative with cancer molecular [ 21].
The example provided had only a single predictor variable, but the results and the general approach also apply to higher order designs where one or more variables could be treated as continuous rather than categorical, leading to analysis of covariance (ANCOVA) or multiple regression-type analyses.
After running GSEA, the leading edge analysis feature of the software was used to examine the genes in the leading edge subsets of selected enriched gene sets.
Specifically, all that growth is leading to outside analysis of Facebook's costs, and when they might need more money.
Theory of the rounding process is presented in detail leading into an analysis of stability.
We develop a spatiotemporal-semantic model to quantitatively express human activity patterns based on topic models, leading to an analysis of space, time and semantics.
Many of the leading candidates for analysis of modal claims are those that explain the truth of modal claims in terms of the literal existence and nature of possible worlds, so without a positive alternative story, it might seem premature to reject this style of explanation of modality.
Case study presentations were followed by discussion, leading to further analysis of primary interactional data.
