Your English writing platform
Discover LudwigExact(1)
The questionnaire began with questions about the respondents: age, sex, length of employment in a leading position (for leaders), length of employment in a hospital, level of education, and area of work.
Similar(59)
Analysis of leader length and velocity can reveal the influence of particular characteristics of lightning overvoltage waveform across the insulators produced by different return-stroke current waveforms in the assessment of the lightning performance of a transmission line.
Moreover, the relative effects of 5' leader length were retained even in the presence of the LNA-AUG1 oligonucleotide.
Mutational, rather than deletional, analysis was performed to maintain sequence length, in view of the potential for influence of translational efficiency by 5'UTR leader length.
In addition, the effects of 5' leader length observed in the plasmid transfection experiments were also seen in the RNA transfections (Figure S3B).
In addition, we observed that increased leader length by itself changed the ratio of the proteins and favored initiation at AUG1.
As with the (CAA)16 5' leader, the mRNA containing the β-globin 5' leader (1.0X), which has approximately equal leader length, expressed the protein from AUG1 at a level ≈3-fold higher than the protein from AUG2.
These observations demonstrate that initiation codon selection is affected by various factors, including AUG codon-accessibility and 5' leader length, and is not necessarily determined by the order of AUG codons (5'→3'→.
The effect of 5' leader length is consistent with our earlier studies [4], and with other studies that have reported effects on translation efficiency and AUG codon choice (e.g. see references [12], [34]).
We report uORFs only from genes where 5' leader length could be confidently determined by empirical data and for which we could calculate Kp/Ku.
We found that the average 5′ leader length of resistant mRNAs is longer (378.5 nt) than that of other mRNAs (169.0 nt), but there is significant variation within both distributions.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com