There is no rationalizing this diabolical dementia which is now seizing our youngest members of Islam, for rationalization leads to justification, which leads to tolerance, which leads to covert approval and ultimately, to overt support.
Given that citrulline-71 in vimentin seems unlikely to lead to tolerance breakdown, the question then arises how does citrullination caused by inflammation break tolerance at all?
Any nicotine exposure can set off mechanisms that lead to tolerance, Dr. Slade said.
In fact, peptide vaccination may lead to tolerance, immunity or even hyper-reactivity causing death of the animals.
Regular use of inhaled β2-agonists might lead to tolerance as reflected in a loss of bronchoprotection.
All of us have knowledge that tends to lead to tolerance; at the same time we have selfish interests that are contradictory to this tolerant ideal.
While it is a common complaint among allergy sufferers, the reality is that taking daily allergy medications does not lead to tolerance.
Unexpectedly, our analyses reveal a stringent threshold of antigen persistence for both prophylactic and therapeutic treatments, although distinct mechanisms lead to tolerance in these two settings.
Furthermore, the authors of the report, Dr. Jordi Cami and Dr. Magi Farré of Barcelona wrote, "Continued use induces adaptive changes in the central nervous system that lead to tolerance, physical dependence, sensitization, craving and relapse".
Like alcoholics, the FH rat drinks excessive amounts of alcohol voluntarily that if allowed to continue will lead to tolerance and dependence, as revealed by anxiety-like behavior upon withdrawal of the alcohol.
