Sentence examples for lead to uncoupling from inspiring English sources
These results suggest that HL Prochlorococcus populations respond quickly to (a biotic changes and the mechanisms that lead to uncoupling between activity and abundance (e.g. density dependent processes) are less important for this community at course molecule scales.
This may lead to uncoupling of the respiratory chain and disruption of membrane-associated processes leading to cell division defects, as observed by electron microscopy.
When the replication fork complex encounters a lesion in the lagging strand, DNA lesions on the lagging strand can lead to uncoupling of the replication complex and the replication complex continues to unwind as leading strand synthesis goes on.
Furthermore, the activation of some, but not all, nutrient signaling pathways may lead to uncoupling of events required for budding from progression past Start.
This might lead to uncoupling of important cellular pathways.
Of note, ONOO− can also directly lead to uncoupling of NOS.
However, manipulation of cell-cycle progression by synchronization led to uncoupling of Cdk1 activity and centrosome separation.
We proposed a model to explain these observations in which failure to replicate G4 motifs in a timely manner leads to uncoupling of the replicative DNA helicase and DNA polymerase resulting in the formation of post-replicative gaps.
GRK5 desensitises the activation of the GPCR signaling pathway by inducing the phosphorylation of agonist-bound GPCR, which in turn leads to uncoupling of the receptor from the G protein and subsequent inhibition of signaling [ 19].
It has been shown that EGF-induced loss of keratinocyte aggregation was mediated by plakoglobin phosphorylation, which led to uncoupling of the desmoglein 2-plakoglobin complex from desmoplakin and thus from the cytoskeleton (Gaudry et al. 2001; Yin et al. 2005).
While most O2– generation in this adherent endothelial cell model undergoing H/R is shown to be initially driven by xanthine oxidase, this in turn leads to eNOS uncoupling through two distinct mechanisms.
