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Any nicotine exposure can set off mechanisms that lead to tolerance, Dr. Slade said.
All of us have knowledge that tends to lead to tolerance; at the same time we have selfish interests that are contradictory to this tolerant ideal.
Furthermore, the authors of the report, Dr. Jordi Cami and Dr. Magi Farré of Barcelona wrote, "Continued use induces adaptive changes in the central nervous system that lead to tolerance, physical dependence, sensitization, craving and relapse".
In fact, peptide vaccination may lead to tolerance, immunity or even hyper-reactivity causing death of the animals.
Regular use of inhaled β2-agonists might lead to tolerance as reflected in a loss of bronchoprotection.
Unexpectedly, our analyses reveal a stringent threshold of antigen persistence for both prophylactic and therapeutic treatments, although distinct mechanisms lead to tolerance in these two settings.
Similar(43)
Substance dependence likely leads to tolerance, in which markedly increased amounts of a drug (or other addictive substance) must be taken to achieve the same effect.
Further, prior exposure to the drug leads to tolerance, rather than sensitization, of the hypolocomotor response to low meth doses.
There is no rationalizing this diabolical dementia which is now seizing our youngest members of Islam, for rationalization leads to justification, which leads to tolerance, which leads to covert approval and ultimately, to overt support.
Antigen presentation by immature DCs leads to tolerance.
This leads to tolerance breaking to this self-protein with consequent development of anti-IFI16 antibodies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com