Ultrasound assessment led to the reclassification of many patients between monarthritis, oligoarthritis and polyarthritis groups.
The use of PSMA PET/CT imaging led to the reclassification of another 14 patients from cN0 to cN1.
These results led to the reclassification of restriction enzymes into restriction phosphodiesterase and glycosylase subgroups [ 7, 8].
The use of DNA-based phylogenetic markers in the past decades therefore led to the reclassification and renaming of numerous fungal species.
Very recently, detailed three-dimensional structural analysis led to the reclassification of several GH5 sequences into family GH30 based on the organization of secondary structural elements around the conserved 8 fold of the catalytic module [ 23].
Recent studies focused on development and functional diversity of innate immune cells have led to the reclassification of these cell types into a large group known as innate lymphoid cells (ILCs) [ 1].
We recognize that classification of isolates and nomenclature for Corynebacterium may have changed over the time period that is encompassed by the source publications included in our analysis, and that new molecular analysis techniques have led to the reclassification of some isolates, and may impact our findings.
However, the latter research has shown that these two genera are heterogeneous and led to the major reclassification resulting in definition of novel genera that include Anaerococcus, Blautia, Finegoldia, Parvimonas, and Peptoniphilus (Murdoch & Shah, 1999; Ezaki et al., 2001; Tindall & Euzeby, 2006; Liu et al., 2008).
It is likely that such reclassification of margin status may lead to the survival differences between revised R0 and R1 resection becoming slightly more pronounced.
These findings could ultimately lead to a reclassification of the higher orders of bacterial viruses, but at present, the genus "Viunalikevirus" will be an independent genus in the family Myoviridae, despite the relationship of its members to the phages of the subfamily Tevenvirinae.
