Sentence examples for lead to the indication from inspiring English sources

There are also questions regarding which PSA values lead to the indication of biopsy when other parameters are normal.

Similarly, improvement in knowledge of coagulation disorders observed in CHS may lead to the indication of replacement therapy with recombinant activated protein C, as reported in severe sepsis [ 12].

In the case presented here, potentially radical resection in a fit-for-surgery patient with a long-term clinical history suggestive of a relatively indolent rectal cancer (associated with a normal CEA serum level) lead to the indication of pneumonectomy for the treatment of an isolated recurrence of rectal cancer involving the main bronchus.

These observations lead to the indication that the time "window" of opportunity to prevent disease in human may share similarities with the NOD mice and thus BCG or other immune-system signalling, safe biological preparation, should be given as therapy before the onset of inflammation of the pancreatic islets (insulitis).

Therefore, one of the reasons for the lack of a preventive analgesic effect could be attributed to the fact that vedaprofen was administered in animals that were already experiencing some pain, considering the discomfort induced by the background disease that led to the indication for the surgical treatment.

The results of the present study then lead to the intriguing indication that well-defined long-range intramolecular interactions could act as regulators of the functional specificity of PrPC.

On the other hand the amount of psychiatric inpatient beds decreased dramatically in Finland in 1990s, and this might have lead to the more stringent indications of hospitalization.

The results of the multicenter studies in Europe eventually lead to the approval of TNF for this indication in Europe (Eggermont et al, 1999).

Monitoring the evolution of alteration mineralogy, microgravity, hydrology and fluid geochemistry could lead to an indication of the most probable locus and timing of a future phreatic eruption.

Its remarkable results led to the worldwide specific indication of OnabotulinumtoxinA for the prevention of headache in CM patients [16].

Most surprisingly, they excluded from their analysis the pivotal, randomized, VELOUR trial, in patients with mCRC who were resistant to or had progressed on a prior oxaliplatin-containing regimen [ 3], which led to the only approved indication for aflibercept.