Sentence examples for lead to the alteration from inspiring English sources

Evolutionary changes to the sequence of the genome will direct reorganization of GRN architectures, which in turn will lead to the alteration of developmental programs.

The variance in liquid liquid demixing velocity at the inner surface of the PVC fibers is influenced by the lumen liquid rate, which can lead to the alteration of pore diameter and pore diameter distribution.

Even though not statistically significant, most changes for vertical parameters were negative in the extraction group, thus showing a vertical decrease, which could lead to the alteration of the gonial angle.

Trimethylamine N-oxide (TMAO), betaine and sarcosine are among the family of methylamines which are a class of osmolytes that may lead to the alteration in the transition behaviour of thermo-responsive polymers (TRPs).

In particular, mutations that lead to the alteration of the stem cell division pattern or the acquisition of some degree of immortality in committed progenitors lead to an early onset of cancer and diminish the impact of genetic instability.

The induced holes in the cell membrane in the presence of Ni nanoparticles could lead to the alteration of permeability of cell membrane and facilitate the drug uptake of quercetin into the cancer cells, which will further induce the apoptosis and/or necrosis of cancer cells.

For a subset of these we provide in vitro evidence that deregulation of the Wnt signalling pathway can lead to the alterations observed in tissues.

Therefore, we selected P. lipolytica as a model to investigate the potential ecological significance of the variants produced during biofilm formation and to explore the genetic changes that lead to the alterations of colony morphology by whole-genome re-sequencing.

In particular, the decrease of mononolinoleoylglycerol might lead to the alterations of triglyceride level, cholesterol metabolism and lipid deposition, which match the necessary conditions for the development of coronary atherosclerosis.

In genetic and surgical disruptions of VNO function that lead to the alterations of innate behaviors, it is often observed that the onset and frequency of specific behaviors, but not the behavioral patterns per se, are altered.

For example, mutation or deletion of the IFN alpha receptor 2 (IFNAR2) can lead to the alterations of IFN- α-mediated transcription, which ultimately causes the IFN- α resistance [ 20].