The exercise successfully stressed procedures for staging the sites and mass dispensing, identified strengths and weaknesses in the dispensing model, and led to substantial revisions in plans for future dispensing.
Consistent evidence from clinical trials investigating the survival benefit of concurrent chemo-radiotherapy on cervical cancer led to substantial revision of treatment guidelines.
This may lead to significant revision (Singer 2005).
Speciation studies have nowadays been fueled by the implementation of molecular studies which often have led to substantial taxonomic revisions.
This can lead to substantial computational savings.
Exercise alone generally doesn't lead to substantial weight loss.
This practice can lead to substantial misclassification.
Government data for new home sales are subject to substantial revisions.
In the pilot phase (which did not lead to any substantial revisions), the entire survey required less than 20 minutes to complete.
The figures are estimates by the Treasury and are subject to substantial revision.
But the discussions with Mr. Ong led to some substantial revisions.
