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Although a large number of CVD risk are described interventions focussed on the major risk factors (smoking, high BP, high LDL cholesterol, low HDL cholesterol and diabetes) have shown to lead to substantial decline in incidence of CVD [ 80].
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However the WHO-recommended 80% coverage and repeated rounds of treatment are projected to lead to substantial declines in trachoma prevalence and may even lead to complete elimination of infection.
And last week, economist Simcha Barkai presented his recent paper at the University of Chicago suggesting corporate concentration leads to substantial declines in money going to workers across the country.
And last week, economist Simcha Barkai presented his recent paper at a conference at the Stigler Center at the University of Chicago, suggesting corporate concentration leads to substantial declines in money going to workers across the country.
Subsequent island-wide mass vaccination (reaching 70% coverage, >200,000 dogs) led to substantial declines in rabies incidence and spread.
The development of antiretroviral therapy (ART) has led to substantial declines in HIV/AIDS-associated morbidity and mortality among many groups in many settings worldwide [ 1].
Further, in Europe and North America, improved emissions controls on coal plants and other major emitters have led to substantial declines in anthropogenic Hg emissions in recent years.
While the use of combination antiretroviral therapy (ART) in individuals infected with human immunodeficiency virus (HIV) has led to substantial declines in disease-related morbidity and mortality [ 1], the benefits have come at a cost.
Early in the 2000s, glitazones were rapidly adopted for use, although subsequent evidence of cardiovascular risks, particularly with rosiglitazone, led to substantial declines in their use during the latter half of the decade (6).
Our results also showed that severe HT (40 °C) led to substantial declines in AsA and AsA/DHA ratio (Fig. 3), which might be one of the ways inducing HT injury probably due to increased oxidation for scavenging overproduced ROS and inefficient AsA GSH cycle.
Based on ecological theory, our expectations are that single or light disturbances may allow for quick recovery of forest structure, whereas intense, repeated, or synergistic disturbances may lead to substantial forest decline and potentially lower carbon states.
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