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For sustained success of the international climate regime, a key question is whether the Paris Agreement with its Intended Nationally Determined Contributions (INDCs), anchored as they are in domestic political realities, can progressively lead to submissions with sufficient ambition?
If, for example, in a system such as that of Australia, if a safety regulator approves 5 clinical indications, this could lead to submissions to a cost-effectiveness evaluator on only one indication with the industry expectation of prescription "leakage" outside recommendations, compromising fiscal savings for the taxpayer.
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Our research program on H5N1 virus transmission, which led to submission of one of the papers that has stirred up so much recent controversy, aimed to investigate whether and how HPAI H5N1 virus can acquire the ability to be transmitted via aerosols among mammals and whether it would retain its virulence.
Interpersonal behavior revolves around the dominant-submissive axes: "One form of behavior tends to elicit its complement: dominance leads to submission and vice versa.
Glare (Fig. 11A) leads to submission without physical interaction.
The ascendency that he gained over her, however, did not lead to her submission.
British officials had assumed, Thant says, that "a swift and simple change at the top would lead to quick submission and the rapid return of normal government".
It is our further hope that the added information will lead to improved submission review times and approvals.
The appropriate selection of patient populations for clinical trials has the potential to lead to earlier regulatory submissions, shorter and more predictable timing to approvals, and faster and more focused product launches.
Subsequent victories in the Middle Atlas restored the French image of superiority in force and led to increasing submissions and the withdrawal of the Zaian deeper into the mountains.
After a shortlist of experienced offshore designers was compiled, funded project definition studies led to the submission of fixed-price tenders for a local build, which maximised the involvement of Australian industry.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com