Sentence examples for lead to structural modifications from inspiring English sources
A growing amount of research demonstrates that OC use may lead to structural modifications in brain regions implicated in high-order cognitive function [ 35], including regional gray matter volumes in regions associated with the fear extinction network such as the prefrontal cortex, anterior cingulate gyrus, cerebellum, and the hippocampus [ 36, 37].
The combination of both physical and chemical reactions in the plasma treatment leads to structural modifications which can be well probed in Raman spectra.
Our study of loblolly pine showed that WEx pretreatment leads to structural modification within the lignin molecule.
Therefore, it is clear that a single oligonucleotide modification can lead to structural changes, modifications in the affinity to bind proteins or in activity that may be relevant to the redox system.
In addition, there is some evidence that horizontally transferred TEs could lead to structural and functional modifications in the recipient species.
New installs in those roles could lead to structural changes.
During PDT, ROS are formed that oxidize a plethora of biomolecules and lead to their structural modification and dysfunction.
The preliminary crystal structure of BthTX-I chemically modified by BPB suggests that the binding of the inhibitor leads to significant structural modifications, especially in the C-terminal region [ 62].
Cleavage of amino acid residues at specific sites in the C-terminal end of αA-crystallin constitutes the major form of modification that leads to structural and functional changes in this sHsp/molecular chaperone [10] [16].
Under conditions of oxidative stress, cysteine modification of KEAP1 leads to structural changes that prevent binding to NRF2, thereby inhibiting NRF2 ubiquitylation resulting in its markedly increased expression [ 44].
It is noticed that some strong interactions via electrostatic attraction, an Au-S linkage or/and irreversible modification are still occurring, which leads to structural changes and subsequent time-dependent enzyme inactivation [20].
