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The markedly increasing number of myofibroblasts during the fibrotic process will lead to structural abnormalities and decreased organ functions, leading inevitably to further disease progression where, for now, artificial or organ replacement therapy is the only outcome.
Reduced ovarian hormone levels associated with menopause or ovariectomy (OVX) not only result in vascular dysfunction but also lead to structural abnormalities in capillaries.
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Many patients with CHF and hyperglycemic symptoms have accompanying abnormalities including obesity, dyslipidemia, and hypertension, which also lead to structural and functional abnormalities of the heart in cardiac dysfunction and CHF [ 3- 6].
Characterization of the interactions among genetics, environmental agents, and time during development that lead to structural or functional abnormalities.
Hypoxia can lead to structural and functional abnormalities in the tumor microvasculature, an adverse diffusion geometry and tumor-related anemia result in a reduced O2 transport capacity of the blood [ 30].
Many patients with CHF and hyperglycemic symptoms have accompanying abnormalities including obesity, dyslipidemia, and hypertension that also lead to structural and functional disorders of heart in cardiac dysfunction and CHF [ 3– 6].
Therefore, functional abnormalities of the lung cells must be assumed which did not lead to structural changes.
These mutation combinations lead to the synthesis of defective type VII collagen and to structural abnormalities in anchoring fibrils.
This is probably due to chronic renal bleeding associated with the inherited coagulopathy which leads to structural renal abnormalities.
New installs in those roles could lead to structural changes.
"Is it due to structural abnormalities in the brain, chemical dysregulation, psychological factors or all three?
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