Sentence examples for lead to small alterations from inspiring English sources

Therefore, while exposure to moderate Glu hyperactivity during embryonic and fetal brain development might lead to small alterations in neural circuitry, these do not translate to the significant transcriptomic changes reported here.

In tumors, changes in gene dosage due to low level copy number alterations may also lead to small alterations in expression of multiple genes, which together could contribute to dysfunction of processes manipulating the genome, resulting in more error prone cell division cycles.

However, mineralogical processes such as (de- carbonatization, silicification, or alteration may leade- carbonatizationfferencesilicificationrorth stalteration Okrusch and maythes 2014).

Even with these numbers, insufficient statistical power may have led to some small alterations in the sex ratio going undetected.

Although changes in the gamma distribution after normalization are relatively small, the alteration of the distribution leads to small mathematical inaccuracies [ 18].

We identified that Brg1/Brm double-mutant mice exhibited increased mitochondrial biogenesis, increases in 'mitophagy', and alterations in mitochondrial fission and fusion that led to small, fragmented mitochondria.

In a few primary metabolic disorders, small genetic mutations lead to structural alterations of specific proteins that disrupt protein function and are responsible for the disease state.

As Pousielle's law dictates, minor changes in caliber of very small diameter capillaries would lead to significant alterations in blood flow.

A recent analysis showed that even relatively small accumulations of genetic polymorphism can lead to substantial alterations in the transcriptome and extracellular secretome of the bacterium, which may lead to altered virulence and changing epidemiology of the infections.

Thus, we believe it is of particular importance to monitor cultured cell lines very closely as small changes to a cell type can lead to major alterations of expression patterns for some non-coding RNAs.

It has been found that even small changes in the structure of the polysaccharide can lead to extensive alterations of chemical and physical properties [ 1].