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Small variations during the process may lead to serious deviations in the API content uniformity of the finished product, particularly if the drug settles fast.
According to eq 2, it can be concluded that nanoparticles of different sizes will have varied lifetimes, and a broad size distribution of nanoparticles will lead to serious deviations from a linear relation in a semilogarithmic plot of PL decay.
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The alignment design with the simultaneous use of the cubic parabola and of the approximate value of the deviation can lead to serious mistakes.
Those models are used in the framework of the HAZOP procedure to determine the magnitude of the deviations from normal operation conditions that may lead to serious accidents and to test design modification to improve the safety characteristic of the process.
The Hazop is applied only to those sections of a plant where it has been determined that a deviation from the design intent could lead to serious accidents; it suggests the action required to reduce the risk of accidents.
Since deviations between the partial pressure of hydrogen and oxygen in PEMFCs lead to serious membrane damage, it is desirable to have a robust and adaptive control to stabilize the partial pressure, which can significantly lengthen their lifetime.
Both Leibniz and Huygens were convinced that all natural change occurs through contact action, and that any deviation from this basic mechanist principle within natural philosophy would lead to serious difficulties, including the revival of outmoded Aristotelian ideas.
These variations can lead to considerable deviations from the outcome of a conventional economic evaluation, which in turn may lead to serious implementation problems at a local level.
But commercial success, alas, can lead to serious difficulties.
But the investigation did not lead to serious parliamentary debate.
Gonorrhoea can also lead to serious problems if left untreated.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com