Sentence examples for lead to rationale from inspiring English sources

However, our study does provide insights into the mechanism that governs downregulation of HR DNA repair genes upon HDAC inhibition, which can lead to rationale usage of HDACis in the clinics.

Third, understanding how Lepidopterans combat virus infection may lead to more rationale design of virus-based 'bioinsecticides' to control pest species.

The discovery of opioid receptors in the spinal cord led to the rationale for the use of intrathecal morphine for pain relief in cancer [ 3].

The discussion leads to a rationale for the use of the combination of theoretical methods to reveal discriminant criteria for toxicity and to analyze the initial steps in the metabolic processes that could yield toxic products.

This led to the rationale of supranormal oxygen delivery, and indeed surgical and trauma patients had better outcome if oxygen delivery was augmented by giving fluids and inotropes [ 4, 5].

More understanding of the mechanism may lead to a more certain rationale for careful induction of NAbs and CTLs by vaccination, maybe potentially capable of synergistic HIV-1 control.

The administration and some senior Israeli security officials have also warned that a military strike would do little to slow the program over the long term, and could lead to war and give Iran rationale to build weapons.

Clarifying a relationship between F-FAMT uptake and the molecular markers including LAT1 may lead to better understanding for the rationale use of F-FAMT PET in patients.

Therefore, two main rationales have lead to the initiation of the present study protocol: 1. Overexpression of EGFR has been shown to influence outcome of EGFR-inhibition in patients with extracranial tumors.

Such a knowledge base will lead to discovery and design of a rationale therapeutic and preventive approach against HSE.

The decision — a response to the NYCLU lawsuit — found that the policy lacked a clear rationale and could lead to "irreparable harm" for children affected by it.