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And without high confidence in the outcome, any implementation would be controversial or indeed lead to overt conflicts — the subject we turn to next.
Furthermore, certain replication timing changes can directly lead to overt genomic instability and may explain unique mutational signatures that are present in cells that have undergone the recently described processes of "chromothripsis" and "kataegis".
In some cases, this can lead to overt pressure from police officers and prosecutors to produce desirable results.
Other studies have found that disclosing mental health conditions on licensure forms can lead to overt or covert professional discrimination, they add.
Gender-variance is perhaps a discrete subset of the same mechanics that lead to overt intersex births, where the processes that fail or trip inadvertently are localized within the developing brain.
Alterations of this regulatory pathway lead to overt neuroinflammation of high pathogenetic impact.
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Results: Transgenic mice with an ectopic p53 gene encoding \ \Delta\ 40p53 developed hypoinsulinemia and glucose intolerance by 3 months of age, which worsened in older mice and led to overt diabetes and premature death from \(\sim\ 14 months of age.
"It makes a person feel cramped and uncomfortable, and this feeling often leads to overt behaviors of being out-of-sorts and general grumpiness, churlishness," says organizational psychologist Billie G. Blair, president of Leading and Learning Inc., a management consulting firm.
The biological cost of increased protection would be a beneficial system gone awry that leads to overt chronic inflammatory disease.
Here we show that PPARα deficiency in the host leads to overt inflammation that suppresses angiogenesis via excess production of the endogenous angiogenesis inhibitor thrombospondin-1 and prevents tumor growth.
Failure of β-cells to meet the demand for increased insulin secretion leads to overt diabetes [ 2- 4].
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CEO of Professional Science Editing for Scientists @ prosciediting.com