"lead to misfortune" is correct and usable in written English.
You can use it when you want to discuss how something can have negative or undesired consequences. For example, "Risk taking behavior can often lead to misfortune."
Any slight difference would lead to trouble and misfortune.
Inappropriate conduct through subverting these gender norms is said to lead to hail and general misfortune.
Our compromising [in allowing entrance to Jewish children] could lead to [the Swiss children's] misfortune".
Fernandez was charged with a flagrant foul, and the French rallied around Parker's misfortune, cutting the lead to 5 within 30 seconds.
The higher values he adopts lead to hundreds of pages largely of misfortune and misery.
Following "California" is Tony Carey's "Room With a View," an unfolding tale of broken dreams and misfortune which eventually lead to homelessness and anguish.
In a report (PDF) posted recently on the Web site of the National Highway Traffic Safety Administration, Lamborghini outlined a kind of thermochemical conga line of misfortune that could potentially lead to a fire.
Non-fulfilment of this procedure may lead to the spirit wandering restlessly and even causing misfortune to the family members as it expresses displeasure.
Wilson writes that Christian Science healing is "not curative ... on its own premises, but rather preventative of ill health, accident and misfortune, since it claims to lead to a state of consciousness where these things do not exist.
The ruined credit that led to their financial misfortune might have been sparkling if only they'd tracked their status on freecreditreport.com.
