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These images show how the tiniest changes (in a protein) can lead to massive effects (a beating heart).
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Many of these drugs appear to have low toxicity profiles, so biological responses are expected below drug concentrations, which lead to massive side effects.
CCl4 is metabolized by hepatocytes, giving rise to toxic trichloromethyl (CCl3) radicals, which mediate cytotoxic effects and eventually lead to massive centrilobular liver necrosis [ 43].
Violent conflicts and internal security dilemmas lead to massive human-rights violations, refugee flows, and spillover effects with the potential to destabilize whole regions.
"Even tiny little vessels, when there are a hundred of them, can lead to massive, massive blood loss quickly".
"These budget proposals will lead to massive changes for the city".
He said if Stormont overspent, it could lead to massive financial penalties.
This could lead to massive problems in the grid, even power outages".
This would lead to massive quid pro quo corruption.
Similarly, interaction of ozone with apoplastic ascorbate could lead to massive transcriptome changes.
However, targeting of B cells with rituximab does not lead to massive antibody reduction.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com