Sentence examples for lead to major differences from inspiring English sources

27 The specific cofactors recruited to PPAR RXR complexes in response to different ligands are suggested to lead to major differences in transactivation of target genes.

These common mechanisms lead to major differences in phenotypic outcomes for muscle tissue structure and organisation and give rise to important consequences for meat nutritional and eating quality.

Representative sampling from the provinces of the Netherlands according to sample size would lead to major differences in numbers of subjects sequenced per region.

Apparently, differences in these cohorts of healthy individuals are substantial and may lead to major differences in the resulting 99th percentiles and therefore the biologically nonequivalent CDV.

Results of >70 % of the post filter samples would lead to major differences in decisions regarding citrate flow depending on the instrument used.

Apparently, differences in these cohorts of healthy individuals are substantial and lead to major differences in the resulting 99th percentiles (the CDV).

This led to major differences in the zeta potential, hydrodynamic size, photocatalytic rate constant, and more importantly, their cytotoxic effects on Hut-78 cancer cells.

Alternatively, the farm environment leads to major differences in diet, age and population structure, immune function, stocking density and behaviours compared with that experienced by wild birds, all of which may affect Campylobacter prevalence and diversity.

The association of CRP with ASDAS improvement led to major differences in outcomes; for example, ASDAS major improvement in HLA-B27-positive patients aged 40 years or less who had BASFI of 4.5 or less and no enthesitis was 81% if their CRP was over 2 mg/dl but only 22% if their CRP was normal.

The use of more and faster whole-body scans within the first hour after injection, as has been published for similar studies with other tracers [ 20, 21], would not have led to major differences in the results because of the near constant uptake in most organs.

Our results (Fig. 2C) suggest that while the small latitudinal shifts required under a low emission scenario would probably have little impact on oak phenology, the shifts of >10° of latitude required under a high emission scenario could lead to major phenological differences between native and climate-matched trees, and significantly dissimilar gallwasp assemblages.