Sentence examples for lead to lineage from inspiring English sources

Whether or not mitotic bookmarking serves to resist cellular reprogramming or stochastic changes in gene expression that might lead to lineage infidelity is amenable to investigation.

These geological events that impede gene flow and lead to strong intraspecific breaks among populations eventually lead to lineage splitting or cladogenesis.

Lastly, evolution of the coding sequences and their regulation following gene duplications have lead to lineage specific partitioning of function or development of new gene functions [ 15, 16].

In EpiSCs, these events do not lead to lineage commitment, probably because of the constraints imposed upon the cells by the pluripotency-promoting culture conditions, raising the possibility that similar constraints may act upon the gastrulation stage epiblast.

However, instances of symbioses that lead to lineage and/or cell fusions between divergent partners (as in the serial endosymbiosis theory for eukaryogenesis, if mitochondria and plastids are no longer considered individual cells) lead to reticulations in the ToCD.

Understanding the evolution of duplicated genes is important because of the hypothesis that gene duplicates provide opportunities for the evolution of reproductive barriers that lead to lineage divergence [ 10], and for the origin of evolutionary novelties [ 1, 11, 12].

Differences in the abundance of T. rotula lineages in the field suggest that past evolutionary events promoting their subdivision have led to lineage designations that are likely ecologically relevant, highlighting that in diatoms, a close interplay of ecology and evolution may regulate their impact on global biogeochemical cycles.

When Olig2, a differentiation-inducing signal, was overexpressed, this led to lineage-specific differentiation of neural stem cells and downregulation of Wnt pathway (i.e., self-renewal pathway) as demonstrated by F3.Olig2.

Compared to other insect genomes, this unusual dominance of mariner elements could be explained by at least three factors acting in concert: i) a long-lasting permissibility of the genome for mariner that leads to lineages with huge copy number.

Thus, it may be the case that TE-derived HS sites provide a specific mechanism that leads to lineage-specific regulatory phenotypes, which in turn are important for the generation of higher level phenotypic differences between species.

iii) frequent occurrence of HT of mariner elements within various species including other insects in particular parasitoids, hematophagous nematodes, parasite worms and a South American bat. a long-lasting permissibility of the genome for mariner that leads to lineages with huge copy number.