Sentence examples for lead to lethality from inspiring English sources

We were surprised to observe that homozygous T-DNA insertions lead to lethality in rice.

Over-expression of this transgene does not lead to lethality or a defect in lifespan (data not shown).

B52 activity is critical for Drosophila development as both loss of function and gain of function lead to lethality [35].

In other kingdoms, H2A.Z has been shown not to be essential in yeast, but mutations in H2A.Z lead to lethality in Tetrahymena [7], Drosophila [8], and mouse [9].

However, mutations leading to highly toxic amyloid would not be found in mammalian since it should lead to lethality early during the developmental process.

However, after phenotypic assortment, we failed to generate a somatic knockout, which indicated that this was probably an essential gene whose knockout would lead to lethality.

One is that overexpression of cellulase results in the degradation of cell wall and leads to lethality of the cell.

CycG inactivation leads to lethality showing that this gene is essential in flies.

We previously showed that using the DI-11 in combination with the UAS-RNAi-HMGCR leads to lethality at 24°C.

Thus, it is possible that disruption of one or more of these additional pathways leads to lethality of the Uch37−/− mice.

Although Grp78+/− heterozygotes are viable and exhibit no phenotypical abnormality, homozygous knockout of Grp78 leads to lethality at embryonic day 3.5 (E3.5) [3.5.