Sentence examples for lead to large scale changes from inspiring English sources

"Weather is chaotic, which means that even a microscopic disturbance can lead to large scale changes.

Global climate change will lead to large scale changes in theirphysical conditions (i.e., circulation, stratification, temperature, and light) and consequently in their biogeochemistry (Steinacher et al. 2010).

"The results may help forecast future forest responses to climate change, and in particular suggest that increased temperatures and changing water availability may lead to large-scale changes in forest composition," notes the report, written by a team of scientists from the University of California and the US Geological Survey.

Such rotations did not lead to large-scale changes in gene expression, indicating that genome folding does not strongly affect gene regulation.

Finally, guest binding by built-in recognition sites can lead to large-scale changes in the volume of the host gel.

Small changes to a 'master switch' can lead to large-scale changes to gene expression resulting in the same tissue on the same organism becoming functionally distinct.

From the results presented in Figure 3, it is clear that small changes in the fitness of the I phenotypes can lead to large-scale changes in populations – even causing transitions from stromal independence to stromagenic tumours.

Indeed, many other Drosophila tumour models such as l(3)mbt, brat, aurA, lgl and aPKCCAAX lead to large-scale changes in gene expression in situ (Carney et al., 2012; Janic et al., 2010).

Mike McKuras, vice president of information technology services at Blue Cross Blue Shield Minnesota, stressed that incremental investments will eventually lead to large-scale change.

The gain or loss of entire chromosomes leads to large-scale changes in gene copy number and expression levels.

We also show that relatively small structural transitions occur at the nucleotide-binding site on Mg-ATP binding, but that these lead to larger scale conformational changes and neck linker docking.