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The conclusion may seem counterintuitive -- that rising diversity should lead to increased segregation.
Critics fear that school choice programs can lead to increased segregation.
The conclusion may seem counterintuitive — that rising diversity should lead to increased segregation.
As I saw from several visits there to my relatives and friends who lived in temporary residences ("Heime") in the city, such camps tend to lead to increased segregation from the local community.
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Our finding, that loss of ATMIN leads to increased segregation errors and micronuclei formation upon replicative stress (Fig. 5C and D), supports this hypothesis.
Consistent with this role in maintaining proper chromosome segregation, HCT116 FBW7 −/− mitotic cells have difficulty aligning their chromosomes at the metaphase plate, which leads to increased segregation errors (Rajagopalan et al. 2004).
One such possibility is that, once hermaphrodites became relatively common, increased segregation of homozygotes would allow efficient purging of deleterious recessive alleles, which would lead to increased selfing rates [ 43- 45].
We hypothesize that alteration of centrosome-related genes cause dysregulation of chromosomal segregation and/or normal DNA damage response, either of which could lead to increased genomic instability in GBM.
Our results suggest that loss of subcortical rich club connectivity in the premanifest stage of Huntington's disease leads to increased network segregation followed by loss of cortical rich club connectivity after clinical disease manifests causing a breakdown of network integration.
This ultimately leads to increased incidences of aneuploidy and chromosome segregation defects [ 44].
These results demonstrate that the vfl2-1 point mutation [ 10] in centrin leads to increased genomic instability via an increase in chromosome loss, suggesting that centrin plays a role in mitotic chromosome segregation.
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