If not, it would only lead to increased burden and harms through overdiagnosis (and treatment) of regressive CIN lesions.
Having a mentally ill family member affects family functioning, which can lead to increased burden on other family members [ 51].
This percentage may be clinically meaningful as such practice could adversely and inordinately influence misdiagnosed patients' health outcomes and lead to increased burden to patients, their caregivers, their physicians and healthcare payers.
An aging population leads to increased burden of chronic diseases, physical disabilities, mental illnesses and other co-morbidities [ 3].
This study provides a foundation for understanding the exposure pathways by which dioxins in soils, sediments, fish and game, and homegrown produce lead to increased body burdens of these compounds.
The insights to be gained from this study will provide a strong foundation for understanding the exposure pathways by which dioxins in soils, sediments, fish and game, and homegrown produce lead to increased body burdens of these compounds, especially in settings where there has been extensive and prolonged environmental contamination.
However, because the body has no physiological mechanism to actively excrete excess iron, repeated blood transfusions lead to increased body iron burden, including iron deposition into the liver, heart and endocrine organs (McLaren et al, 1983).
Consequently, while having an important role in the clearance of virus in infected heart tissue, virus-specific immune cells such as T and B cells may at the same time lead to increased tissue damage and burden for the host.
This disproportionate burden can lead to increased exposure to harmful environmental conditions and chemical, physical, and biological agents for impacted communities [ 1, 2, 26- 28].
51, 52 Acting through diverse biological mechanisms, the HIV virus influences the brain's immune system, and the increased inflammatory disease burden may lead to increased risk of depression and other mood and psychotic symptoms.
In our experience, harmonizing the screening process to a shared reference protocol lead to increased productivity with a reduced time burden on any particular participant, maintaining peak observational skills of the participating scientists.
