Sentence examples for lead to improved efficacy from inspiring English sources
New bowel cleansers for colonoscopy that lead to improved efficacy, safety, and tolerability are needed.
The development of particulate bone void fillers with added biological function to augment skeletal tissue formation will lead to improved efficacy in bone replacement surgery.
Interventions probably lead to improved efficacy and safety of pharmacotherapy, although future controlled research will have to prove to what extent drug-induced harm is prevented.
Pericyte coverage can reduce tumor vessel vulnerability to VEGF inhibition, and in such cases, targeting treatments against both pericytes and endothelial cells may lead to improved efficacy [ 55].
Hence, gastric cancer harbors attractive molecular targets for therapy with HSP-90 inhibitors, which could lead to improved efficacy of antineoplastic therapy regimens [ 36].
While SFK inhibitors administered in combination with other agents may show that these drugs have synergistic effects, a recent study showed that sequential treatment involving chemotherapy followed by SFK inhibitors lead to improved efficacy [ 8].
If validation of the models is successful, the next step will be to run a clinical trial to test if the use of the model for the development of foot and ankle orthoses leads to improved efficacy.
Due to the very limited data regarding the safety of high doses of allopurinol in patients with renal insufficiency, allopurinol dosing in this population remains controversial [ 49], and we cannot speculate whether allopurinol dose titration in the CONFIRMS study, and more specifically among this elderly subgroup, would have led to improved efficacy without increased AEs.
Moving forward, we believe that utilization of SPR in the screening and design of nanoRx has the potential to greatly improve the development of targeted nanoRx formulations and eventually lead to improved therapeutic efficacy.
It remains to be investigated whether this will lead to improved treatment efficacy without raising concern about toxicity.
Such results could lead to improved therapeutic efficacy.
