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That would lead to higher total taxes for such households.
Patches maintain a steadier level, but, over time, this can lead to higher total exposure to the drug.
Including the costs of these activities would lead to higher total outbreak costs and a higher ROI.
These "hidden costs" lead to higher total therapy costs of (generic) docetaxel compared to the EGFR TKI therapy erlotinib, that largely consist of drug costs which are transparent and easier to predict for the health care payers.
Although the drug costs of erlotinib are higher than generic docetaxel (incremental €3770): the costs of intravenous chemotherapy administration (incremental −€4510), and the costs of adverse event therapy (incremental −€837) lead to higher total therapy costs for docetaxel compared to the epidermal growth factor receptor tyrosine kinase inhibitor therapy erlotinib.
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Certain enzyme defects can impair homocysteine metabolism and lead to high total homocysteine levels.
We show that reward is as effective as punishment for maintaining public cooperation and leads to higher total earnings.
Meal-time ingestion of caloric beverages, milk, orange juice and regular cola, led to higher total meal-time energy intakes compared to either water or diet cola.
Computation experiments are performed to illustrate the effect of the stage duration on the two objective values, and the results show that longer stage duration leads to higher total unmet demand and total fuel and CO2 emission cost.
Sharing of resources between applications leads to higher total resource utilization and thereby to less waste.
Those with more land, livestock and cash are more likely to diversify their income by investing surplus (pull factor), which leads to higher total income.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com