Endotoxin administration led to flu-like symptoms.
They fear that such a development could lead to a flu pandemic like the one that killed tens of millions of people in 1918 and 1919.
The next criticism that may be aimed at the Department of Health could be that a full-time, director-level lead dedicated to flu preparedness and resilience is only now being appointed.
DENV infection is usually asymptomatic or may lead to uncomplicated "flu-like" disease with fever, myalgia, arthralgia and rash.
But the researchers hope that their approach might one day lead to a "universal" flu vaccine that would provide long-term protection against flu viruses.
If that became routine, it could lead to much wider flu protection because schoolchildren often are the vectors that infect their families.
However, scientists fear that if airborne transmission became possible it would lead to a deadly flu pandemic killing millions of people because most of the individuals who are known to have been infected with H5N1 die from the virus.
(These symptoms, echoing those of mild flu, lead to the persistent but false rumor that flu shots cause flu, experts say).
In 2004, British regulators forced the closing of Chiron's factory in Liverpool because of quality problems, which led to a flu vaccine shortfall in the United States last year.
This can lead to mastitis, a flu-like condition, and breast abscesses, a painful collection of pus that forms in the breast, according to the academy.
