Sentence examples for lead to fibrotic changes from inspiring English sources

EMT under pathological processes could lead to fibrotic changes.

Rempel et al. have shown that repetition rate or number of loading cycles is associated with increased tendon microtears in a dose response pattern, and that these early microstructural changes in repetitively loaded tendons may initiate degenerative processes that lead to fibrotic and disruptive tissue changes [ 98- 102].

Despite significant advances in the understanding of tissue responses to biomaterials, most implants are still plagued by inflammatory responses which can lead to fibrotic encapsulation.

In turn, cyclooxygenase-2 (COX-2) and its major metabolite, PGE2, lead to fibrotic scar formation in fetal skin.

Also, paracicatrical emphysema adjacent to fibrotic changes may appear as cystic spaces.

Furthermore, the lymphatic network has been reported to be enlarged according to fibrotic changes in cirrhotic rats [ 5].

Therefore, we investigated whether AngII/AT1R is associated with changes in kidney responsiveness due to fibrotic changes from previous I/R injury.

Whatever the cause, this inflammation may in some instances lead to a fibrotic change that ultimately interferes with gas exchange.

While regeneration fully recovers wounds with architecture and functionality identical to unwounded skin, repair leads to fibrotic tissue accumulation that forms a scar.

This eventually leads to fibrotic remodelling of the liver with the final risk of hepatocellular carcinoma (HCC) development.

Overexpression of COL1A1 leads to fibrotic diseases like the dermal fibrosis found in aging as well as in RDEB.