Sentence examples for lead to efficacy from inspiring English sources

Low RRs from CT-based trials could lead to efficacy underestimation of potentially active targeted treatments and maybe in withdrawal rather than further testing 14, 15.

These promising results led to efficacy studies administering systemic treatment with an anticancer siRNA, siPlk1-polyplex, which inhibited tumor growth by 73%and87%7% compared with siCtrl-polyplex or saline-treated mice, respectively, leading to prolonged overall survival.

3 The spread of antimalarial drug resistance over the past few decades has led to efficacy monitoring being intensified to enable early detection of resistance.

Both approaches excluded those lost to follow-up due to lack of efficacy from statistical analyses, which may lead to biased efficacy estimates [ 8].

The pre-clinical data shown here support the view that combining conventional drugs with netrin-1 interference could lead to superior efficacy as well as a reduction of chemotherapy doses at increased efficacy.

The most common resistance mutations which would lead to decreased efficacy of Atripla are M184V/I (leading to emtricitabine resistance), K103N (efavirenz resistance), and K65R (tenofovir resistance).

But the efficacy of most herbal medications is influenced by many factors which may lead to unstable efficacy in clinical practice.

New bowel cleansers for colonoscopy that lead to improved efficacy, safety, and tolerability are needed.

In general, a broad distribution of DAR can lead to reduced efficacy, and thus the distribution needs to be tightly controlled.

The development of particulate bone void fillers with added biological function to augment skeletal tissue formation will lead to improved efficacy in bone replacement surgery.

Drug combinations target at different pathways of cells can potentially lead to higher efficacy and lower toxicity due to drug synergy.