Treatment of human head and neck squamous cell carcinoma (HNSCC) imposes a major challenge for clinicians and patients, as primary surgery, especially in advanced stages, can cause severe disability, while chemotherapy and irradiation can lead to dreadful early and late toxicity.
Hyperglycemia can lead to dreadful complications of Diabetic Ketoacidosis (where the byproducts of fat-breakdown accumulate) so quickly that you may not suspect it.
Monopolies led to dreadful service and a tradition of demanding bribes to make it less so: a few thousand naira to have a telephone line installed in days rather than years, a few thousand more to get power lines mended.Past attempts at reform have failed, not least because so many Nigerians in top positions have benefited personally from bad policies.
With equal economy, particularly in the clipped dialogue, Kingsnorth keeps up the pace: the killing of a shaven-headed Norman thegn – "with my scramasax i saws up until his throta is cut and blaec blud then cums roarin out lic gathran wind" – leads to dreadful reprisals for an innocent hamlet.
"I think we have to begin to deal with the perception that a few isolated instances of player misconduct lead to a dreadful stereotyping by the media of what it is to be an N.B.A. player," said Stern, acknowledging his league's image problems.
Instead, a dreary start by the Yankees led to a dreadful finish as the Arizona Diamondbacks won Game 6 of the World Series, 15-2.
They fear that their hopeful but fragile coalition government, led by Fuad Siniora, may collapse, giving way to a renewal of the sectarian tensions that led to a dreadful civil war between 1975 and 1990, which in turn led to a venal Syrian overlordship that ended only a year ago.Rockets rain on IsraelHizbullah has a militia.
He also brought to Villa Park an excitement and unpredictability that had been absent since the days of Martin O'Neill; despite the bizarre tactical decisions that led to a dreadful run of one point from 27, Villa under Sherwood was a lot of fun.
Continuing on, but essentially staying in one place, leads to that dreadful refrain at midlife, "Oh no, this can't be all there is!" You end up stagnated and stuck in a rut. 3.
Pro-penny forces like Americans for Common Cents cite tradition and their belief that rounding prices to the nearest nickel, as urged by those who find the penny dreadful, would inevitably lead to higher prices.
On Radio 4 yesterday a former teacher, Matthew Wren, recounted how after being accused of shoving a 15-year-old student who came at him as he tried to break up a scuffle, he was suspended for months, a dreadful experience that lead to him leaving the profession.
