Sentence examples for lead to dramatic effects from inspiring English sources
Due to close energies of interaction between different paraffin-like components, minor changes of experimental conditions may lead to dramatic effects.
Relatively subtle changes in the proportion of mutant mtDNA can lead to dramatic effects on a patient's phenotype; however, the mtDNA mutation doesn't do it alone.
The aerodynamic efforts generated in these situations may induce undesired lateral deviations, which can lead to dramatic effects, if the driver is surprised.
The present study provides the first evidence that Pten haploinsufficiency leads to insulin hypersensitivity in vivo, suggesting that even small changes in Pten levels or activity can lead to dramatic effects on insulin responses.
In fact, lack of autophagy has been already reported to not always lead to dramatic effects; for example, atg7−/− flies do not show any developmental defect and are fully viable.
The present data also provides an indication of a putative defect in GAG sulfation, which may lead to dramatic biological effects, as exemplified by mutations in PAPSS2, SLC26A2, gPAPP or SUMF1, all causing skeletal dysplasias [41] [44].
In addition, reduced levels of Gpr52 were observed to lead to dramatic protective effects in neurons derived from the stem cells of a patient with Huntington's disease.
These effects lead to dramatic changes in root system architecture that significantly impact aboveground plant growth.
Our experiments also demonstrate that, despite the simplicity of the present system, the origins of wettability alteration are rather complex and that synergistic effects can lead to dramatic variations such as the unexpectedly high contact angle at 60 °C.
It was found that even relatively modest neuroprotective effects on BCU counts can lead to dramatic reductions in incidence rates of Alzheimer's disease.
The model shows that even modest neuroprotective effects on basic cognitive units can lead to dramatic reductions in the number of Alzheimer's cases.
