The phrase "lead to disuse" is correct and usable in written English.
You can use it to describe a situation in which something is used less and less over time. For example, "The lack of spare parts for the old model of car has led to its disuse."
For instance, a net decrease in protein synthesis and/or a net increase in protein degradation can lead to disuse atrophy.
Pain from any cause, such as overuse or injury, such as repetitive overhead motions from sporting activities, work tasks or daily chores, may lead to disuse or weakness of the cuff.
Reduced weight bearing due to pain from osteoarthritis of the hip (OAH) could lead to disuse of the affected lower limb and result in lower bone mineral density (BMD) and muscle mass.
Looking at the substance of the programme, it is implausible that the provision of only one or two hours of home help services per week would lead to disuse syndrome.
In contrast, prolonged absence of mechanical loading (bed rest) leads to disuse osteoporosis [10].
As pain leads to disuse as well as muscle inhibition, this weakness has been thought to be a consequence of pain and disuse in OA [ 13- 15].
This could lead to a disuse pattern that may increase the likelihood of injury from common activities of daily living.
Beginning with an overview of the general risks of automation that can lead to misuse, disuse and abuse by the user, the chapter then turns to human automation function allocation, which is both a design and user concern.
Specifically, fear-avoidance theory asserts that catastrophizing about pain leads to pain-related fear (e.g. fear of movement) and avoidance/escape behaviours (e.g. passive pain coping) that lead to disability, disuse, and further pain [ 14, 15].
Both continuous pain and signs of 'cold dystrophy' can lead to assumed irreversible disuse.
The initial stages of motor function decline are exacerbated in elderly individuals in whom these early declines lead to further muscular disuse.
