The disrupted architecture may lead to disruption of critical cellular maturational interactions mediated by cytokine homeostasis [53].
There is also a risk of systemic absorption of corticosteroids, which can lead to disruption of normal physiological steroid production.
"We saw the film and decided it could not be released as it was due to fears that it would lead to disruption of public order.
Central necrosis may lead to disruption of a friable feeding artery [7].
It lies mainly in strand fragmentation [22] and also can lead to disruption of bonds between strands in double-stranded DNA [23].
Loss-of-function (LOF) (i.e., nonsense, splice site, and frameshift) variants that lead to disruption of gene function are likely to contribute to the etiology of neuropsychiatric disorders.
Surgical interventions that lead to disruption of the blood supply to the ovaries or involve direct damage to ovarian tissue may be expected to lead to a reduction in the primordial follicle pool.
If pathogenic, AAbs binding to proteins in optic nerve neurons may lead to disruption of protein function, apoptosis of cells, as well as inhibiting enzymes that preserve neuronal glycolytic activity and neuronal integrity.
Results can be used to identify and visually examine building zones where long-term occupancy may lead to disruption of the circadian system in the absence of supplemental electrical lighting capable of effective circadian stimulus.
These groups believe the law will lead to disruption of existing health plans, increased costs from new insurance standards, and that it will increase the deficit.
The same reasoning can be applied to the inference of recombination cold spots, regions where recombination might lead to disruption of protein function [43].
