"lead to disintegration" is a correct and usable phrase in written English.
It means to cause something to break down or fall apart. Example: The constant fighting and lack of communication in their relationship eventually led to its disintegration.
Yet epidemics of riot, disease, and labor conflict led some to wonder whether growth would lead to disintegration.
Appearing in the same year as Betty Friedan's The Feminine Mystique and a year after Doris Lessing's The Golden Notebook, The Bell Jar was part of that revolution – but also a book of biting wit, mordant social observation, and a moving exploration of how a search for integrity can lead to disintegration.
The degradation and resorption of calcium orthophosphate coatings, films and layers in a biological environment could lead to disintegration of the coating, resulting in the loss of both coating-substrate bond strength and the implant fixation.
Mass spectrometry matrix-assisted laser desorption/ionization-time-of-flight (MALDI-TOF) performed on a sample containing a collection of drops obtained from the surface of the functionalized glass provided evidence that the irradiation lead to disintegration of the ICs and therefore exit of the octylamine molecule (the guest) from the cyclodextrin cavity (the matrix).
These processes eventually lead to disintegration of the cell wall.
They initiate chain reactions which lead to disintegration of cell membranes and cell compounds, including lipids, proteins and nucleic acids.
The supposed diffusion of gold atoms leads to disintegration of the initial multilayer structure.
Annealing leads to disintegration of the initially continuous gold layer and formation of gold nanoclusters.
Phosphorylation by protein kinases or cleavage by proteases leads to disintegration of PPC/gene complexes and gene expression.
It was hypothesized that the breakdown of macro-aggregates and diminished binding agents leads to disintegration of the soil matrix which releases the labile carbon to a free state; this in turn increases its loss substantially from soil.
We found that it was critical to deliver TRPM8 to the final step of purification in its tetrameric form, since altering different conditions, such as ionic strength, osmotic pressure or detergents led to disintegration of tetramers into the lower assemblies, and ultimately to monomers.
