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A difference in inflammatory response and endothelial dysfunction between these two forms of PAH may lead to different changes in the PA wall that might explain the difference found in the patterns of PA dilation.
At the location of the temperature step, compressive stresses occur in the circumferential direction at one element, and tensile stresses at the other element, which lead to different changes in the wall thickness due to Poisson's ratio effects.
Different metal surfaces and clearance diameters will confer different fluid dynamics, friction, and wear characteristics to the joint and may therefore lead to different changes in bone density.
As a result, the overexpression or suppression of different miRNA members in a miRNA family could lead to different changes in the expression levels of the target genes.
Studied doses of stress treatments deleteriously affect the organism's viability and lead to different changes of both general and specific cellular stress response mechanisms.
It is also worthwhile to consider that long-term p30 expression has been documented to induce cell cycle alterations, which may also lead to different changes in gene expression [ 21].
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Different health-related behavior patterns led to different changes in weight status and SRH and these differences were sex- and age specific.
It is possible that the IM process would have led to different changes in the protocol if stakeholders from other companies were involved.
Over the years, these surprising results led to different changes in practice guidelines; specifically, the recent 2014 American College of Cardiology/American Heart Association (ACC/AHA) guidelines recommend that perioperative β-blockers should be started only in patients considered to be at intermediate or high risk for myocardial ischemia [ 9].
Binding sites variation affecting the enhancers sequence can lead to different epigenetic changes and bring cells to differently act.
In future work, RNAseq, proteomics and metabolomics studies of these SCRaMbLEd strains or others will help us better understand how various deletions and rearrangements on synthetic chromosomes lead to different phenotypic changes.
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