Sentence examples for lead to destabilisation from inspiring English sources
But last weekend Mr Kostunica dashed any hope that such demands would be satisfied in the near future: hasty changes at the top would "inevitably lead to destabilisation" and could "endanger democratic change," he argued.Respectfully but firmly, many of Mr Kostunica's political allies disagree.
These observations are consistent with the notion of cancer as a 'systems disease' that involves changes that lead to destabilisation of the GRN.
Increasing population and construction of roads have led to destabilisation of slopes, thus leading to mass wasting and movement, further aggravation due to recent events of cloud bursts and unprecedented flash floods.
These results suggest that in vivo depletion of each of the LSU r-proteins examined leads to destabilisation and degradation of the LSU and/or its precursors.
In vivo depletion of the analysed LSU r-proteins was lethal and led to destabilisation and degradation of the LSU and/or its precursors.
Expression of activated Rac1 or activated PAK1 K299R) in keratinocytes leads to destabilisation of the E-cadherin/catenin complexes [ 43].
This is consistent with the hypothesis that EphA signalling via Vav2 and RhoA leads to destabilisation of microtubules and allows cells to repel after contact with one another.
The reverse mutation, K109I in AVR4 and K111I in avidin, led to destabilisation of the proteins, resulting in a 1.9°C and 7.0°C decrease in the Tm, respectively.
Inactivation of this gene, which resulted from bialleleic hypermethylation of the promoter, leads to destabilisation of simple DNA repeat sequence in colorectal tumours (Cunningham et al, 1998; Herman et al, 1998).
Loss of APC function leads to destabilisation of the 'destruction complex', a multiprotein complex encompassing three scaffold proteins, APC, Axin1, and Axin2 (conductin), and two kinases, glycogen synthase kinase-3 β (GSK3 β) and casein kinase 1 (CK1).
"It could lead to major destabilisation of societies and also political destabilisation," said Piot. "It is going to come at a very high cost.
