Sentence examples for lead to deactivation from inspiring English sources

Counteracting kinases are phosphatases, which generally lead to deactivation of a phosphorylated protein [4], and for normal development of a cell (and hence a healthy state of the organism) fine-tuning of phosphorylation and dephosphorylation processes is of crucial importance [4].

Increase level of GPx (Glutathione Peroxidase) which lead to deactivation of LPO reactions.

Deactivation of STAT6 was predicted due to repression of MHC-II class genes which are known to be regulated by STAT6 [ 35], as well as the expression of SOCS1, which has been reported to lead to deactivation of STAT6 [ 36].

By-products as oligomer, produced by oligomerization of olefin, blocked or covered the pores, led to deactivation of catalysts.

As thermally induced sintering of the nanoparticles leads to deactivation of the catalyst, an approach is used where the nanoparticles are linked via organic molecules (ligands) binding to the particle surface to form a highly porous "ligand-linked" nanoparticle network.

Further support comes from XPS data, showing that, after reaction Fe-MT still features only Fe(III) species, whereas V species in V-MT are basically reduced to V(IV), which leads to deactivation of these samples.

This may be due to pore blockage during the glycerol hydrogenolysis reaction which leads to deactivation of the catalyst.

As reported by Rabeah and co-workers [15], in the case of PNP/Cr catalytic system, a (PNP Cr II)(CH3 2 complex stemmed from Cr III) species is regarded as the active species for selective tetramerization by passing a reversible redox cycle, while reduction to Cr(I) leads to deactivation.

Opioid receptors are generally considered inhibitory receptors and one could assume that binding of inhibitory receptors leads to deactivation; however, molecular studies in rats show that opioid receptor binding can lead to both inhibition and excitation.

These data establish that activation of HIF-1α leads to deactivation of CAFs under hypoxic conditions.

Further studies have demonstrated that Thr308 phosphorylation is necessary and sufficient for AKT activation and that dephosphorylation at Thr308 alone leads to deactivation of AKT.