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We demonstrate how the bistable nature of the lac operon's feedback, when perturbed by patterning lactose (inducer) and glucose (inhibitor), can lead to coordination of cell expression patterns across a field in ways that mimic motifs seen in developmental biology.
We were surprised by the observation that the bistable nature of the lac operon's feedback system, when perturbed by patterns of lactose (inducer) and glucose (inhibitor), can lead to coordination of cell expression patterns across a field in ways that mimic motifs seen in developmental biology.
The challenge is that the functional groups must selectively react with just one metal component [i.e., coordination of either metal to both coordination groups (which would lead to coordination polymers) must be avoided].
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Instead of the top-down integration approach where abrupt and artificial integration of central ministries leads to coordination of specific systems, the basic stance is that inducing the integration of supervising ministries while adjusting specific systems serving as a major cause of conflict on the site would be more effective.
We become too specialised in everything, which eventually leads to coordination issues".
Although the tetra-equatorial isomer is the dominant form in solution, the addition of Pt II) led to coordination, and a preference for the tetra-axial form, the better to bind the metal ion.
Such cell-to-cell coupling leads to coordination between beta cells with more homogeneous cellular responses as measured by NAD(P H activity [ 13] and cell calcium signals [ 14, 15].
Tapia et al.'s (2012) two case studies on humanitarian coordination offer a possible explanation for the failure of information systems to lead to enhanced coordination despite explicit efforts.
Colorado's public health department issued an advisory about the dangers of drinking water containing THC, warning it could lead to impaired coordination while driving and psychotic symptoms.
I think we will make some machinery-of-government changes that do meet the criteria I have set out that it will bring greater focus or lead to better coordination.
In such an alkaline medium, the amide-NH2 side group is deprotonated, which may lead to other coordination modes.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com