"lead to an end" is correct and usable in written English.
You can use it when referring to the completion or conclusion of something. For example, "The negotiations lead to an end with both sides coming to an agreement."
"Did that recognition lead to an end of the occupation?
The review could lead to an end to Austria's political isolation within the European Union.
They hoped this would lead to an end of the controversy.
Both companies said they expected the agreement to lead to an end to the legal dispute.
After the first step of the classification using the full feature set, the high confidence recognition result will lead to an end of the recognition process.
If the Fed sees economic recovery, that is likely to lead to an end to the Fed support that the market has been so reliant on.
Republican leaders said today that the Senate amendment would be stripped from the military bill, a decision that is likely to lead to an end-of-the-year confrontation with President Clinton.
The decision of Carnegie's patron, Leeds Metropolitan University, to withdraw the club's bid to join the Football Association's new Super League is set to lead to an end-of-season exodus of players and quite possibly the folding of the club known as Leeds United before it was jettisoned from the Elland Road set-up two years ago.
It's possible the whole process would lead to an end-of-year continuing resolution, which would continue current spending policies until the next president takes office (unlike a budget and spending bills, which Republicans could actually shape).
As known, acute and long-term severe liver disease mainly including alcoholic and viral hepatitis can lead to an end-stage function failure.
Although the linear RNA amplification used in our approach may lead to a 3' end bias in the transcript molecules, comparative analyses are possible with careful primer design.
