Treatment with Astragalus did lead to additional changes in gene expression as compared to Sambucus, indicated by a few genes induced 3 10 fold specifically by Astragalus.
Furthermore, the inflammatory nature of the tumour microenvironment can lead to additional genetic changes in cells associated with malignancy.
In addition, it seems likely that CSCs, like their normal stem cell counterparts, have a deficiency in the decatenation checkpoint, and that this deficiency could lead to additional genetic changes and increased tumour malignancy.
In addition to altering mRNA levels, estrogen can activate signaling pathways [ 7, 36] that alter protein PTMs [ 37, 38], which can lead to additional estrogen-dependent changes in cardiac function.
The start of an inquiry by the New York attorney general's office into Exxon Mobil's record on climate change could lead to additional legal actions involving other major energy companies.
Gen. Eric H. Holder Jr. are expected to be released Tuesday, which could lead to additional firings, disciplinary action and structural changes to Uber's workplace.
This triadic approach to delivering lifestyle behaviour change support may lead to additional challenges for paediatric health professionals compared to those working in adult acute care settings.
Of greater concern is the possibility that some matching variables may have been directly related to HRQOL change, which could lead to additional bias [ 35].
"Ransom payments lead to future kidnappings, and future kidnappings lead to additional ransom payments.
The change would most likely cause Regents exams, now held just before graduation, to be held earlier in the spring and could lead to additional costs for districts.
