Sentence examples for lead to abnormality from inspiring English sources

Genome instability could lead to abnormality of nuclear structure, while excessive protein aggregation could cause ER malfunction.

It has been suggested that alteration in TPH2 gene expression might result in central serotonergic system dysfunction, which may in turn lead to abnormality of behavior and increased susceptibility to psychiatric disorders such as TS [ 27].

Since low levels of CCTα lead to abnormalities of cilia tips (Figure 2L and M) and mutant cells also have abnormal tips we decided to investigate if the mutated form of CCTα was targeted to cilia.

Aberrant protein isoforms can lead to abnormalities in protein function and may even result in genetic disorders or cancer.

Perhaps they are a presage to Seralini et al. indicating that some features of rat chow can lead to abnormalities in sensitive animals.

Shortening through compression might lead to abnormalities at the wrist (creating an ulna minus or ulna plus), needing a secondary shortening or lengthening operation.

At a dimensional level, childhood trauma may lead to abnormalities in affect regulation, impulse control and cognitive functioning that could reduce the ability to cope with later environmental risk factors (cannabis misuse, stressful life events).

But when the researchers performed DNA analyses, they found that 52% of sperm from diabetic men contained fragmented DNA, which could prevent them from fertilizing an egg or lead to abnormalities in the offspring.

Inflammation of the meninges may lead to abnormalities of the cranial nerves, a group of nerves arising from the brain stem that supply the head and neck area and which control, among other functions, eye movement, facial muscles, and hearing.

The reduction of these connections in the schizophrenic model may lead to abnormalities in this process.

Mutations of Notch receptors and ligands in mice lead to abnormalities in many tissues, including the vascular system.